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Design, Synthesis, and Validation of a Branched Flexible Linker for Bioactive Peptides
[Image: see text] A branched flexible linker that incorporates a fluorescent dansyl moiety was synthesized and used to connect two high affinity NDP-α-MSH ligands or two low affinity MSH(4) ligands. The linker was incorporated into the conjugate by solid-phase synthesis. In vitro biological evaluati...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538035/ https://ncbi.nlm.nih.gov/pubmed/17279799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo062276g |
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