A Sucrose-derived Scaffold for Multimerization of Bioactive Peptides

A spherical molecular scaffold bearing eight terminal alkyne groups was synthesized in one step from sucrose. One or more copies of a tetrapeptide azide, either N(3)(CH(2))(5)(C=O)-His-dPhe-Arg-Trp-NH(2) (MSH4) or N(3)(CH(2))(5)(C=O)-Trp-Met-Asp-Phe-NH(2) (CCK4), were attached to the scaffold via th...

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Detaylı Bibliyografya
Asıl Yazarlar: Rao, Venkataramanarao, Alleti, Ramesh, Xu, Liping, Tafreshi, Narges K., Morse, David L., Gillies, Robert J., Mash, Eugene A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197697/
https://ncbi.nlm.nih.gov/pubmed/21940174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.08.053
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