Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRC(S96A) variant overexpression

The histidine-rich calcium binding protein (HRC) Ser96Ala polymorphism was shown to correlate with ventricular arrhythmias and sudden death only in dilated cardiomyopathy patients but not in healthy human carriers. In the present study, we assessed the molecular and cellular mechanisms underlying hu...

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Detalhes bibliográficos
Main Authors: Han, Peidong, Cai, Wenfeng, Wang, Yanru, Lam, Chi Keung, Arvanitis, Demetrios A., Singh, Vivek P., Chen, Shan, Zhang, Huiliang, Zhang, Rongli, Cheng, Heping, Kranias, Evangelia G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Cardiac Excitation and Contraction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197373/
https://ncbi.nlm.nih.gov/pubmed/21742996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01153.2010
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