Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia

Precise Ca cycling through the sarcoplasmic reticulum (SR), a Ca storage organelle, is critical for proper cardiac muscle function. This cycling initially involves SR release of Ca via the ryanodine receptor, which is regulated by its interacting proteins junctin and triadin. The sarco/endoplasmic r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pollak, Adam J., Haghighi, Kobra, Kunduri, Swati, Arvanitis, Demetrios A., Bidwell, Philip A., Liu, Guan-Sheng, Singh, Vivek P., Gonzalez, David J., Sanoudou, Despina, Wiley, Sandra E., Dixon, Jack E., Kranias, Evangelia G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576816/
https://ncbi.nlm.nih.gov/pubmed/28784772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706441114
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