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Some Human Immunodeficiency Virus Type 1 Vpu Proteins Are Able To Antagonize Macaque BST-2 In Vitro and In Vivo: Vpu-Negative Simian-Human Immunodeficiency Viruses Are Attenuated In Vivo

Human immunodeficiency virus type 1 (HIV-1) Vpu enhances the release of viral particles from infected cells by targeting BST-2/tetherin, a cellular protein inhibiting virus release. The widely used HIV-1(NL4-3) Vpu functionally inactivates human BST-2 but not murine or monkey BST-2, leading to the n...

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Autors principals: Shingai, Masashi, Yoshida, Takeshi, Martin, Malcolm A., Strebel, Klaus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196440/
https://ncbi.nlm.nih.gov/pubmed/21775449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00626-11
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