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Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs

BST-2/CD317/tetherin is a host transmembrane protein that potently inhibits human immunodeficiency virus type 1 (HIV-1) virion release by tethering the nascent virions to the plasma membrane. Viral protein U (Vpu) is an accessory protein encoded by HIV-1 as well as by some simian immunodeficiency vi...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Yao, Weitong, Yoshida, Takeshi, Hashimoto, Saki, Takeuchi, Hiroaki, Strebel, Klaus, Yamaoka, Shoji
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955256/
https://ncbi.nlm.nih.gov/pubmed/31666374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01669-19
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