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Differential Effects of Human Immunodeficiency Virus Type 1 Vpu on the Stability of BST-2/Tetherin

BST-2/CD317/tetherin is a host factor that inhibits the release of HIV-1 and other unrelated viruses. A current model proposes that BST-2 physically tethers virions to the surface of virus-producing cells. The HIV-1-encoded Vpu protein effectively antagonizes the activity of BST-2. How Vpu accomplis...

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Detalhes bibliográficos
Main Authors: Andrew, Amy J., Miyagi, Eri, Strebel, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067951/
https://ncbi.nlm.nih.gov/pubmed/21191020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02080-10
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