The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

BACKGROUND: The Human Immunodeficiency virus type 1 (HIV-1) Vpu protein enhances virus release from infected cells and induces proteasomal degradation of CD4. Recent work identified BST-2/CD317 as a host factor that inhibits HIV-1 virus release in a Vpu sensitive manner. A current working model prop...

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Hlavní autoři: Andrew, Amy J, Miyagi, Eri, Kao, Sandra, Strebel, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754425/
https://ncbi.nlm.nih.gov/pubmed/19737401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-80
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