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Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion

HIV-1 Vpu enhances the release of virions from infected cells. Recent work identified Bst-2/CD317/tetherin as a host factor whose inhibitory activity on viral release is counteracted by Vpu. A current working model proposes that Bst-2 inhibits virus release by tethering viral particles to the cell s...

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Detalhes bibliográficos
Main Authors: Miyagi, Eri, Andrew, Amy J., Kao, Sandra, Strebel, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650357/
https://ncbi.nlm.nih.gov/pubmed/19196977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813223106
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