BST-2 Mediated Restriction of Simian-Human Immunodeficiency Virus

Pathogenic simian-human immunodeficiency viruses (SHIV)contain HIV-1 Vpu and SIV Nef, both shown to counteract BST-2 (HM1.24; CD317; tetherin) inhibition of virus release in a species-specific manner. We show that human and pig-tailed BST-2 (ptBST-2) restrict SHIV. We found that sequential “humanize...

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Detalhes bibliográficos
Main Authors: Ruiz, Autumn, Lau, David, Mitchell, Richard S., Hill, M. Sarah, Schmitt, Kimberly, Guatelli, John C., Stephens, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104713/
https://ncbi.nlm.nih.gov/pubmed/20708210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.021
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