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BST-2 Mediated Restriction of Simian-Human Immunodeficiency Virus
Pathogenic simian-human immunodeficiency viruses (SHIV)contain HIV-1 Vpu and SIV Nef, both shown to counteract BST-2 (HM1.24; CD317; tetherin) inhibition of virus release in a species-specific manner. We show that human and pig-tailed BST-2 (ptBST-2) restrict SHIV. We found that sequential “humanize...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104713/ https://ncbi.nlm.nih.gov/pubmed/20708210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.021 |
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