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Requirements of the Membrane Proximal Tyrosine and Dileucine Based Sorting Signals for Efficient Transport of the Subtype C Vpu Protein to the Plasma Membrane and in Virus Release

Previously, we showed that the Vpu protein from HIV-1 subtype C is more efficiently transported to the cell surface than the well studied subtype B Vpu (Pacyniak et al., 2005) and that a SHIV expressing the subtype C Vpu exhibited a decreased rate of CD4(+) T-cell loss following inoculation in macaq...

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Detalhes bibliográficos
Main Authors: Ruiz, Autumn, Hill, M. Sarah, Schmitt, Kimberly, Guatelli, John, Stephens, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104992/
https://ncbi.nlm.nih.gov/pubmed/18579178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.05.022
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