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Modulation of the severe CD4(+) T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C HIV-1 clinical isolate

Previously, we showed that the Vpu protein from subtype C human immunodeficiency virus type 1 (HIV-1) was efficiently targeted to the cell surface, suggesting that this protein has biological properties that differ from the well-studied subtype B Vpu protein. In this study, we have further analyzed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hill, M. Sarah, Ruiz, Autumn, Pacyniak, Erik, Pinson, David M., Culley, Nathan, Yen, Bonnie, Wong, Scott W., Stephens, Edward B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727868/
https://ncbi.nlm.nih.gov/pubmed/17950774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.09.015
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