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Simian-Human Immunodeficiency Viruses Expressing Chimeric Subtype B/C Vpu Proteins Demonstrate the Importance of the Amino Terminal and Transmembrane Domains in the Rate of CD4(+) T Cell Loss in Macaques

Previously, we reported that simian-human immunodeficiency viruses expressing either the lab adapted subtype B (SHIV(KU-1bMC33)) or subtype C (SHIV(SCVpu)) Vpu proteins of human immunodeficiency virus type 1 (HIV-1) had different rates of CD4(+) T cell loss following inoculation into macaques. In th...

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Detalhes bibliográficos
Main Authors: Ruiz, Autumn, Schmitt, Kimberly, Culley, Nathan, Stephens, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104993/
https://ncbi.nlm.nih.gov/pubmed/23218949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.10.030
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