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Identification of Amino Acids within the Second Alpha Helical Domain of the Human Immunodeficiency Virus type 1 Vpu that are Critical for Preventing CD4 Cell Surface Expression
Human immunodeficiency virus type 1 (HIV-1) encodes for a Vpu protein, which interacts with CD4 resulting in its degradation. In this study, we examined the role of the ten amino acids within the predicted second α-helical domain of the subtype B Vpu cytoplasmic tail in CD4 down-modulation using a V...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104991/ https://ncbi.nlm.nih.gov/pubmed/19944437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.10.048 |
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