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Low-pH-Dependent Changes in the Conformation and Oligomeric State of the Prefusion Form of Herpes Simplex Virus Glycoprotein B Are Separable from Fusion Activity

The cellular requirements for activation of herpesvirus fusion and entry remain poorly understood. Low pH triggers change in the antigenic reactivity of the prefusion form of the herpes simplex virus (HSV) fusion protein gB in virions, both in vitro and during viral entry via endocytosis (S. Dollery...

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Detalhes bibliográficos
Main Authors: Dollery, Stephen J., Wright, Catherine C., Johnson, David C., Nicola, Anthony V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196434/
https://ncbi.nlm.nih.gov/pubmed/21813610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05291-11
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