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Low-pH-Dependent Changes in the Conformation and Oligomeric State of the Prefusion Form of Herpes Simplex Virus Glycoprotein B Are Separable from Fusion Activity

The cellular requirements for activation of herpesvirus fusion and entry remain poorly understood. Low pH triggers change in the antigenic reactivity of the prefusion form of the herpes simplex virus (HSV) fusion protein gB in virions, both in vitro and during viral entry via endocytosis (S. Dollery...

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Bibliografiske detaljer
Main Authors: Dollery, Stephen J., Wright, Catherine C., Johnson, David C., Nicola, Anthony V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196434/
https://ncbi.nlm.nih.gov/pubmed/21813610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05291-11
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