Cargando...

Acidic pH Mediates Changes in Antigenic and Oligomeric Conformation of Herpes Simplex Virus gB and Is a Determinant of Cell-Specific Entry

Herpes simplex virus (HSV) is an important human pathogen with a high worldwide seroprevalence. HSV enters epithelial cells, the primary site of infection, by a low-pH pathway. HSV glycoprotein B (gB) undergoes low pH-induced conformational changes, which are thought to drive membrane fusion. When n...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Weed, Darin J., Dollery, Stephen J., Komala Sari, Tri, Nicola, Anthony V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096812/
https://ncbi.nlm.nih.gov/pubmed/29925660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01034-18
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!