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Low pH-Induced Conformational Change in Herpes Simplex Virus Glycoprotein B

Herpesviruses can enter host cells using pH-dependent endocytosis pathways in a cell-specific manner. Envelope glycoprotein B (gB) is conserved among all herpesviruses and is a critical component of the complex that mediates membrane fusion and entry. Here we demonstrate that mildly acidic pH trigge...

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Detalhes bibliográficos
Main Authors: Dollery, Stephen J., Delboy, Mark G., Nicola, Anthony V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849479/
https://ncbi.nlm.nih.gov/pubmed/20147407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02573-09
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