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Reversible conformational change in herpes simplex virus glycoprotein B with fusion-from-without activity is triggered by mildly acidic pH

BACKGROUND: The pre-fusion form of the herpes simplex virus (HSV) fusion protein gB undergoes pH-triggered conformational change in vitro and during viral entry (Dollery et al., J. Virol. 84:3759-3766, 2010). The antigenic structure of gB from the fusion-from-without (FFWO) strain of HSV-1, ANG path...

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Detalhes bibliográficos
Main Authors: Siekavizza-Robles, Carlos R, Dollery, Stephen J, Nicola, Anthony V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003269/
https://ncbi.nlm.nih.gov/pubmed/21122119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-352
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