Local Elongation of Endothelial Cell-anchored von Willebrand Factor Strings Precedes ADAMTS13 Protein-mediated Proteolysis

Platelet-decorated von Willebrand factor (VWF) strings anchored to the endothelial surface are rapidly cleaved by ADAMTS13. Individual VWF string characteristics such as number, location, and auxiliary features of the ADAMTS13 cleavage sites were explored here using imaging and computing software. B...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: De Ceunynck, Karen, Rocha, Susana, Feys, Hendrik B., De Meyer, Simon F., Uji-i, Hiroshi, Deckmyn, Hans, Hofkens, Johan, Vanhoorelbeke, Karen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Enzymology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196129/
https://ncbi.nlm.nih.gov/pubmed/21896483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.271890
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