Single Particle Tracking of ADAMTS13 (A Disintegrin and Metalloprotease with Thrombospondin Type-1 Repeats) Molecules on Endothelial von Willebrand Factor Strings

von Willebrand factor (VWF) strings are removed from the endothelial surface by ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type-1 repeats)-mediated proteolysis. To visualize how single ADAMTS13 molecules bind to these long strings, we built a customized single molecule fluoresce...

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Detalhes bibliográficos
Main Authors: De Ceunynck, Karen, Rocha, Susana, De Meyer, Simon F., Sadler, J. Evan, Uji-i, Hiroshi, Deckmyn, Hans, Hofkens, Johan, Vanhoorelbeke, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979392/
https://ncbi.nlm.nih.gov/pubmed/24550384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535963
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