Polo-like Kinase 1 Facilitates Loss of Pten Tumor Suppressor-induced Prostate Cancer Formation

Loss of the tumor suppressor Pten (phosphatase and tensin homolog deleted on chromosome 10) is thought to mediate the majority of prostate cancers, but the molecular mechanism remains elusive. In this study, we demonstrate that Pten-depleted cells suffer from mitotic stress and that nuclear function...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, X. Shawn, Song, Bing, Elzey, Bennett D., Ratliff, Timothy L., Konieczny, Stephen F., Cheng, Liang, Ahmad, Nihal, Liu, Xiaoqi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195584/
https://ncbi.nlm.nih.gov/pubmed/21890624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.269050
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