Cotargeting Polo-Like Kinase 1 and the Wnt/β-Catenin Signaling Pathway in Castration-Resistant Prostate Cancer

The Wnt/β-catenin signaling pathway has been identified as one of the predominantly upregulated pathways in castration-resistant prostate cancer (CRPC). However, whether targeting the β-catenin pathway will prove effective as a CRPC treatment remains unknown. Polo-like kinase 1 (Plk1) is a critical...

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Publicado no:Mol Cell Biol
Main Authors: Li, Jie, Karki, Anju, Hodges, Kurt B., Ahmad, Nihal, Zoubeidi, Amina, Strebhardt, Klaus, Ratliff, Timothy L., Konieczny, Stephen F., Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648817/
https://ncbi.nlm.nih.gov/pubmed/26438599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00825-15
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