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The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection

The Apobec3 family of cytidine deaminases can inhibit the replication of retroviruses and retrotransposons. Human and chimpanzee genomes encode seven Apobec3 paralogs; of these, Apobec3DE has the greatest sequence divergence between humans and chimpanzees. Here we show that even though human and chi...

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Detalles Bibliográficos
Main Authors: Duggal, Nisha K., Malik, Harmit S., Emerman, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194980/
https://ncbi.nlm.nih.gov/pubmed/21835794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05046-11
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