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The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection

The Apobec3 family of cytidine deaminases can inhibit the replication of retroviruses and retrotransposons. Human and chimpanzee genomes encode seven Apobec3 paralogs; of these, Apobec3DE has the greatest sequence divergence between humans and chimpanzees. Here we show that even though human and chi...

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Bibliografische gegevens
Hoofdauteurs: Duggal, Nisha K., Malik, Harmit S., Emerman, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194980/
https://ncbi.nlm.nih.gov/pubmed/21835794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05046-11
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