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Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G

Host genomes have adopted several strategies to curb the proliferation of transposable elements and viruses. A recently discovered novel primate defense against retroviral infection involves a single-stranded DNA-editing enzyme, APOBEC3G, that causes hypermutation of HIV. The HIV-encoded virion infe...

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Detalhes bibliográficos
Main Authors: Sawyer, Sara L, Emerman, Michael, Malik, Harmit S
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479043/
https://ncbi.nlm.nih.gov/pubmed/15269786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020275
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