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Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates

Host-virus arms races are inherently asymmetric; viruses evolve much more rapidly than host genomes. Thus, there is high interest in discovering mechanisms by which host genomes keep pace with rapidly evolving viruses. One family of restriction factors, the APOBEC3 (A3) cytidine deaminases, has unde...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yang, Lei, Emerman, Michael, Malik, Harmit S, McLaughlin, Richard N
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263822/
https://ncbi.nlm.nih.gov/pubmed/32479260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58436
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