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The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection
The Apobec3 family of cytidine deaminases can inhibit the replication of retroviruses and retrotransposons. Human and chimpanzee genomes encode seven Apobec3 paralogs; of these, Apobec3DE has the greatest sequence divergence between humans and chimpanzees. Here we show that even though human and chi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3194980/ https://ncbi.nlm.nih.gov/pubmed/21835794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05046-11 |
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