Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

Administration of typical antipsychotic drugs, such as haloperidol, promotes cAMP-dependent signaling in the medium spiny neurons (MSNs) of the striatum. In this study, we have examined the effect of haloperidol on the state of phosphorylation of the ribosomal protein S6 (rpS6), a component of the s...

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Bibliografiska uppgifter
Huvudupphovsmän: Valjent, Emmanuel, Bertran-Gonzalez, Jesus, Bowling, Heather, Lopez, Sébastien, Santini, Emanuela, Matamales, Miriam, Bonito-Oliva, Alessandra, Hervé, Denis, Hoeffer, Charles, Klann, Eric, Girault, Jean-Antoine, Fisone, Gilberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194082/
https://ncbi.nlm.nih.gov/pubmed/21814187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.144
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