Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

Administration of typical antipsychotic drugs, such as haloperidol, promotes cAMP-dependent signaling in the medium spiny neurons (MSNs) of the striatum. In this study, we have examined the effect of haloperidol on the state of phosphorylation of the ribosomal protein S6 (rpS6), a component of the s...

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Main Authors: Valjent, Emmanuel, Bertran-Gonzalez, Jesus, Bowling, Heather, Lopez, Sébastien, Santini, Emanuela, Matamales, Miriam, Bonito-Oliva, Alessandra, Hervé, Denis, Hoeffer, Charles, Klann, Eric, Girault, Jean-Antoine, Fisone, Gilberto
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194082/
https://ncbi.nlm.nih.gov/pubmed/21814187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.144
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