Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

Administration of typical antipsychotic drugs, such as haloperidol, promotes cAMP-dependent signaling in the medium spiny neurons (MSNs) of the striatum. In this study, we have examined the effect of haloperidol on the state of phosphorylation of the ribosomal protein S6 (rpS6), a component of the s...

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Detalhes bibliográficos
Main Authors: Valjent, Emmanuel, Bertran-Gonzalez, Jesus, Bowling, Heather, Lopez, Sébastien, Santini, Emanuela, Matamales, Miriam, Bonito-Oliva, Alessandra, Hervé, Denis, Hoeffer, Charles, Klann, Eric, Girault, Jean-Antoine, Fisone, Gilberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194082/
https://ncbi.nlm.nih.gov/pubmed/21814187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.144
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