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Structure of the NH(2)-terminal variable region of cardiac troponin T determines its sensitivity to restrictive cleavage in pathophysiological adaptation

We previously reported that the NH(2)-terminal variable region of cardiac troponin T (cTnT) is removed by restrictive μ-calpain cleavage in myocardial ischemia-reperfusion (Zhang, Biesiadecki, Jin, Biochemistry 45:11681–94, 2006). Selective removal of the NH(2)-terminal variable region of cTnT had a...

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Библиографические подробности
Главные авторы: Zhang, Zhiling, Feng, Han-Zhong, Jin, J.-P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192527/
https://ncbi.nlm.nih.gov/pubmed/21924234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.08.013
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