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Selective deletion of the NH(2)-terminal variable region of cardiac troponin T in ischemia-reperfusion by myofibril-associated μ-calpain cleavage

The structure of the NH(2)-terminal region of troponin T (TnT) is hypervariable among the muscle type-specific isoforms and is also regulated by alternative RNA splicing. This region does not contain binding sites for other thin filament proteins but alteration of its structure affects the Ca(2+)-re...

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Hlavní autoři: Zhang, Zhiling, Biesiadecki, Brandon J., Jin, Jian-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762003/
https://ncbi.nlm.nih.gov/pubmed/16981728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060273s
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