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Selective deletion of the NH(2)-terminal variable region of cardiac troponin T in ischemia-reperfusion by myofibril-associated μ-calpain cleavage
The structure of the NH(2)-terminal region of troponin T (TnT) is hypervariable among the muscle type-specific isoforms and is also regulated by alternative RNA splicing. This region does not contain binding sites for other thin filament proteins but alteration of its structure affects the Ca(2+)-re...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1762003/ https://ncbi.nlm.nih.gov/pubmed/16981728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060273s |
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