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Restricted N-terminal truncation of cardiac troponin T: a novel mechanism for functional adaptation to energetic crisis

The N-terminal variable region of cardiac troponin T (TnT) is a regulatory structure that can be selectively removed during myocardial ischaemia reperfusion by μ-calpain proteolysis. Here we investigated the pathophysiological significance of this post-translational modification that removes amino a...

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Detalhes bibliográficos
Main Authors: Feng, Han-Zhong, Biesiadecki, Brandon J, Yu, Zhi-Bin, Hossain, M Moazzem, Jin, J-P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538805/
https://ncbi.nlm.nih.gov/pubmed/18556368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153577
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