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Restricted N-terminal truncation of cardiac troponin T: a novel mechanism for functional adaptation to energetic crisis
The N-terminal variable region of cardiac troponin T (TnT) is a regulatory structure that can be selectively removed during myocardial ischaemia reperfusion by μ-calpain proteolysis. Here we investigated the pathophysiological significance of this post-translational modification that removes amino a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538805/ https://ncbi.nlm.nih.gov/pubmed/18556368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153577 |
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