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Ca(2+)-induced delayed afterdepolarizations are triggered by dyadic subspace Ca(2+) affirming that increasing SERCA reduces aftercontractions

Ca(2+)-induced delayed afterdepolarizations (DADs) are depolarizations that occur after full repolarization. They have been observed across multiple species and cell types. Experimental results have indicated that the main cause of DADs is Ca(2+) overload. The main hypothesis as to their initiation...

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Detalhes bibliográficos
Main Authors: Fink, Martin, Noble, Penelope J., Noble, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191104/
https://ncbi.nlm.nih.gov/pubmed/21666112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01055.2010
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