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Lower sarcoplasmic reticulum Ca(2+) threshold for triggering afterdepolarizations in diabetic rat hearts
BACKGROUND: Type-2 diabetes (T2D) increases the arrhythmias risk through incompletely elucidated mechanisms. Ventricular arrhythmias could be initiated by delayed afterdepolarizations (DADs) resulting from elevated spontaneous sarcoplasmic reticulum (SR) Ca(2+) release (SR Ca(2+) leak). OBJECTIVE: T...
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| Publicado no: | Heart Rhythm |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6491240/ https://ncbi.nlm.nih.gov/pubmed/30414461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2018.11.001 |
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