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Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents?

Early afterdepolarizations (EADs) have been implicated in severe cardiac arrhythmias and sudden cardiac deaths. However, the mechanism(s) for EAD genesis, especially regarding the relative contribution of Ca(2+) wave (CaW) vs. L-type Ca current (I(Ca,L)), still remains controversial. In the present...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhao, Zhenghang, Wen, Hairuo, Fefelova, Nadezhda, Allen, Charelle, Baba, Akemichi, Matsuda, Toshio, Xie, Lai-Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330805/
https://ncbi.nlm.nih.gov/pubmed/22307670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00742.2011
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