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Diurnal Regulation of the Early Growth Response 1 (Egr-1) Protein Expression by Hepatocyte Nuclear Factor 4α (HNF4α) and Small Heterodimer Partner (SHP) Cross-talk in Liver Fibrosis

Early growth response 1 (Egr-1) protein is a critical regulator of genes contributing to liver fibrosis; however, little is known about the upstream transcriptional factors that control its expression. Here we show that Egr-1 expression is tightly regulated by nuclear receptor signaling. Hepatocyte...

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Detalhes bibliográficos
Main Authors: Zhang, Yuxia, Bonzo, Jessica A., Gonzalez, Frank J., Wang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191004/
https://ncbi.nlm.nih.gov/pubmed/21725089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253039
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