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Characterization of the Mitochondrial Localization of the Nuclear Receptor SHP and Regulation of Its Subcellular Distribution by Interaction with Bcl2 and HNF4α

The nuclear receptor small heterodimer partner SHP was shown recently to translocate to the mitochondria, interact with Bcl2, and induce apoptosis in liver cancer cells. However, the exact mitochondrial localization of SHP remains to be determined. In addition, the detailed interaction domains betwe...

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Detalhes bibliográficos
Main Authors: Zhang, Yuxia, Wang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706418/
https://ncbi.nlm.nih.gov/pubmed/23874642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068491
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