Embryonic but Not Postnatal Reexpression of Hepatocyte Nuclear Factor 1α (HNF1α) Can Reactivate the Silent Phenylalanine Hydroxylase Gene in HNF1α-Deficient Hepatocytes

The failure to transcribe the phenylalanine hydroxylase (PAH) gene in the liver of hepatocyte nuclear factor 1α (HNF1α)-deficient mice correlated with DNA hypermethylation and the presence of an inactive chromatin structure (M. Pontoglio, D. M. Faust, A. Doyen, M. Yaniv, and M. C. Weiss, Mol. Cell....

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Viollet, Benoît, Yaniv, Moshe, Pontoglio, Marco
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11340160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.11.3662-3670.2001
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