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Arginine Methylation of the Nuclear Poly(A) Binding Protein Weakens the Interaction with Its Nuclear Import Receptor, Transportin

The nuclear poly(A) binding protein, PABPN1, promotes mRNA polyadenylation in the cell nucleus by increasing the processivity of poly(A) polymerase and contributing to poly(A) tail length control. In its C-terminal domain, the protein carries 13 arginine residues that are all asymmetrically dimethyl...

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Bibliografiska uppgifter
Huvudupphovsmän: Fronz, Katharina, Güttinger, Stefan, Burkert, Kerstin, Kühn, Uwe, Stöhr, Nadine, Schierhorn, Angelika, Wahle, Elmar
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190935/
https://ncbi.nlm.nih.gov/pubmed/21808065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273912
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