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Transportin2 functions as importin and mediates nuclear import of HuR

The RanGTP-binding nuclear transport receptors transportin1 (TRN1) and transportin2 (TRN2) are highly similar in sequence but are reported to function in nuclear import and export, respectively. Here we show that TRN2 possesses properties of a nuclear import receptor. TRN1/2 both interacted with a s...

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Detalhes bibliográficos
Main Authors: Güttinger, Stephan, Mühlhäusser, Petra, Koller-Eichhorn, Roland, Brennecke, Julius, Kutay, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365720/
https://ncbi.nlm.nih.gov/pubmed/14981248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400342101
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