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Transportin2 functions as importin and mediates nuclear import of HuR

The RanGTP-binding nuclear transport receptors transportin1 (TRN1) and transportin2 (TRN2) are highly similar in sequence but are reported to function in nuclear import and export, respectively. Here we show that TRN2 possesses properties of a nuclear import receptor. TRN1/2 both interacted with a s...

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Библиографические подробности
Главные авторы: Güttinger, Stephan, Mühlhäusser, Petra, Koller-Eichhorn, Roland, Brennecke, Julius, Kutay, Ulrike
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC365720/
https://ncbi.nlm.nih.gov/pubmed/14981248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400342101
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