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Importin 7 and Importin α/Importin β Are Nuclear Import Receptors for the Glucocorticoid Receptor

The vertebrate glucocorticoid receptor (GR) is cytoplasmic without hormone and localizes to the nucleus after hormone binding. GR has two nuclear localization signals (NLS): NL1 is similar in sequence to the SV40 NLS; NL2 is poorly defined, residing in the ligand-binding domain. We found that GR dis...

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Bibliografiske detaljer
Main Authors: Freedman, Neal D., Yamamoto, Keith R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404022/
https://ncbi.nlm.nih.gov/pubmed/15004228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0839
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