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Importin 7 and Importin α/Importin β Are Nuclear Import Receptors for the Glucocorticoid Receptor

The vertebrate glucocorticoid receptor (GR) is cytoplasmic without hormone and localizes to the nucleus after hormone binding. GR has two nuclear localization signals (NLS): NL1 is similar in sequence to the SV40 NLS; NL2 is poorly defined, residing in the ligand-binding domain. We found that GR dis...

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Autors principals: Freedman, Neal D., Yamamoto, Keith R.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC404022/
https://ncbi.nlm.nih.gov/pubmed/15004228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0839
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