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Transportin2 functions as importin and mediates nuclear import of HuR

The RanGTP-binding nuclear transport receptors transportin1 (TRN1) and transportin2 (TRN2) are highly similar in sequence but are reported to function in nuclear import and export, respectively. Here we show that TRN2 possesses properties of a nuclear import receptor. TRN1/2 both interacted with a s...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Güttinger, Stephan, Mühlhäusser, Petra, Koller-Eichhorn, Roland, Brennecke, Julius, Kutay, Ulrike
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981248/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400342101
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