Poly(A) Tail Length Is Controlled by the Nuclear Poly(A)-binding Protein Regulating the Interaction between Poly(A) Polymerase and the Cleavage and Polyadenylation Specificity Factor

Poly(A) tails of mRNAs are synthesized in the cell nucleus with a defined length, ∼250 nucleotides in mammalian cells. The same type of length control is seen in an in vitro polyadenylation system reconstituted from three proteins: poly(A) polymerase, cleavage and polyadenylation specificity factor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kühn, Uwe, Gündel, Miriam, Knoth, Anne, Kerwitz, Yvonne, Rüdel, Sabine, Wahle, Elmar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
RNA: Processing and Catalysis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755688/
https://ncbi.nlm.nih.gov/pubmed/19509282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018226
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