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Arginine Methylation of the Nuclear Poly(A) Binding Protein Weakens the Interaction with Its Nuclear Import Receptor, Transportin

The nuclear poly(A) binding protein, PABPN1, promotes mRNA polyadenylation in the cell nucleus by increasing the processivity of poly(A) polymerase and contributing to poly(A) tail length control. In its C-terminal domain, the protein carries 13 arginine residues that are all asymmetrically dimethyl...

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Detalhes bibliográficos
Main Authors: Fronz, Katharina, Güttinger, Stefan, Burkert, Kerstin, Kühn, Uwe, Stöhr, Nadine, Schierhorn, Angelika, Wahle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190935/
https://ncbi.nlm.nih.gov/pubmed/21808065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273912
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