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Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins

Botulinum neurotoxins (BoNTs) and tetanus neurotoxin are the causative agents of the paralytic diseases botulism and tetanus, respectively. The potency of the clostridial neurotoxins (CNTs) relies primarily on their highly specific binding to nerve terminals and cleavage of SNARE proteins. Although...

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Autors principals: Benson, Marc A., Fu, Zhuji, Kim, Jung-Ja P., Baldwin, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190786/
https://ncbi.nlm.nih.gov/pubmed/21849494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.272054
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