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Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins

Botulinum neurotoxins (BoNTs) and tetanus neurotoxin are the causative agents of the paralytic diseases botulism and tetanus, respectively. The potency of the clostridial neurotoxins (CNTs) relies primarily on their highly specific binding to nerve terminals and cleavage of SNARE proteins. Although...

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Detalhes bibliográficos
Main Authors: Benson, Marc A., Fu, Zhuji, Kim, Jung-Ja P., Baldwin, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190786/
https://ncbi.nlm.nih.gov/pubmed/21849494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.272054
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