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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

Tetanus neurotoxin (TeNT) is an exotoxin produced by Clostridium tetani that causes paralytic death to hundreds of thousands of humans annually. TeNT cleaves vesicle-associated membrane protein-2, which inhibits neurotransmitter release in the central nervous system to elicit spastic paralysis, but...

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Hlavní autoři: Chen, Chen, Fu, Zhuji, Kim, Jung-Ja P., Barbieri, Joseph T., Baldwin, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785345/
https://ncbi.nlm.nih.gov/pubmed/19602728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027391
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