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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

Tetanus neurotoxin (TeNT) is an exotoxin produced by Clostridium tetani that causes paralytic death to hundreds of thousands of humans annually. TeNT cleaves vesicle-associated membrane protein-2, which inhibits neurotransmitter release in the central nervous system to elicit spastic paralysis, but...

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Autori principali: Chen, Chen, Fu, Zhuji, Kim, Jung-Ja P., Barbieri, Joseph T., Baldwin, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785345/
https://ncbi.nlm.nih.gov/pubmed/19602728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027391
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