Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

Tetanus neurotoxin (TeNT) is an exotoxin produced by Clostridium tetani that causes paralytic death to hundreds of thousands of humans annually. TeNT cleaves vesicle-associated membrane protein-2, which inhibits neurotransmitter release in the central nervous system to elicit spastic paralysis, but...

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Autors principals: Chen, Chen, Fu, Zhuji, Kim, Jung-Ja P., Barbieri, Joseph T., Baldwin, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Protein Synthesis, Post-Translational Modification, and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785345/
https://ncbi.nlm.nih.gov/pubmed/19602728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027391
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